Description

n-Nitrosopyrrolidine is a potent nitrosamine compound of significant interest in research and analytical chemistry. Its primary value lies in its role as a critical reference standard and analytical marker for detecting and quantifying nitrosamine impurities in pharmaceuticals, food, and consumer products. This compound is essential for laboratories and manufacturers requiring high-purity analytical standards to ensure product safety and regulatory compliance, particularly in the pharmaceutical and food safety sectors.

Application

• Pharmaceutical Impurity Testing: Serves as a certified reference material (CRM) for the identification and quantification of nitrosamine impurities in active pharmaceutical ingredients (APIs) and finished drug products, supporting compliance with stringent regulatory guidelines (e.g., FDA, EMA).
• Food Safety Analysis: Used as an analytical standard in methods to detect volatile nitrosamines in foodstuffs, beverages, and food-contact materials to assess contamination risks.
• Environmental Monitoring: Employed in research and testing laboratories to analyze nitrosamine levels in water, soil, and air samples as part of environmental health and safety studies.
• Chemical Research: Acts as a key reagent and model compound in organic synthesis and mechanistic studies related to nitrosation chemistry, carcinogenesis, and metabolic pathways.
• Quality Control & Method Development: Essential for developing, validating, and calibrating analytical methods such as GC-MS, LC-MS/MS, and HPLC in quality control laboratories.

Basic Information

Product Name	n-Nitrosopyrrolidine
CAS No.	930-55-2
Molecular Formula	C₄H₈N₂O
Molecular Weight	100.12 g/mol
Synonyms	N-Nitrosopyrrolidine; 1-Nitrosopyrrolidine; N-NP; N-Nitrosotetramethylenimine; Pyrrolidine, 1-nitroso-; Tetramethylenimine, N-nitroso-; NSC 8548; Nitrosopyrrolidine
EINECS	213-217-1

Quality Control

Our n-Nitrosopyrrolidine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and precise purity determination by chromatographic techniques, to ensure it meets the high standards required for reference materials. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results for identity, assay, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Yellow to orange liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.