Description

3-Fluoro-n-Acetylneuraminic Acid is a fluorinated derivative of the essential sialic acid, N-acetylneuraminic acid, designed for advanced biochemical research and pharmaceutical development. This compound is a critical building block for studying and modulating sialidase (neuraminidase) enzyme activity, which is pivotal in numerous biological and pathological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for drug discovery, enzyme inhibition studies, and the synthesis of novel glycoconjugates.

Application

• Enzyme Inhibition Studies: Serves as a potent and specific inhibitor for neuraminidase/sialidase enzymes in biochemical assays.
• Antiviral Research: Investigated as a precursor or analog in the development of novel antiviral agents targeting influenza and other viruses.
• Glycobiology Research: A key intermediate for synthesizing fluorinated sialoglycoconjugates to study cell-cell recognition, signaling, and immune response.
• Pharmaceutical Intermediates: Used in the research and development of new therapeutic compounds, including potential cancer therapeutics and anti-inflammatory drugs.
• Diagnostic Reagent Development: Employed in creating specialized reagents for enzymatic detection kits and diagnostic assays.
• Biochemical Tool Compound: Provides a stable, fluorinated probe for metabolic pathway analysis and mechanistic studies in microbiology and cell biology.

Basic Information

Product Name	3-Fluoro-n-Acetylneuraminic Acid
CAS No.	921-40-4
Molecular Formula	C11H18FNO9
Molecular Weight	327.26 g/mol
Synonyms	3-Fluoro-N-acetylneuraminic acid; 3-Fluorosialic acid; 3-F-Neu5Ac; 3-Fluoro-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid; 3-Fluoro-5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid; 3-Fluoro-DANA; Fluoroneuraminic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Fluoro-n-Acetylneuraminic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.