Description

7-Methoxy-1-[(4-Methylphenyl)Sulfonyl]-2,3-Dihydroquinolin-4(1H)-One is a high-purity sulfonamide derivative and a key synthetic intermediate in advanced organic chemistry. This compound is valued for its precise molecular structure, which serves as a critical building block in the development of complex active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex quinoline and sulfonamide-based molecular architectures.
• Material Science Precursor: Investigated for the synthesis of advanced organic materials, including ligands for catalysts and functional polymers.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratory settings.

Basic Information

Product Name	7-Methoxy-1-[(4-Methylphenyl)Sulfonyl]-2,3-Dihydroquinolin-4(1H)-One
CAS No.	901-90-6
Molecular Formula	C18H17NO4S
Molecular Weight	343.40 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-7-methoxy-2,3-dihydro-4(1H)-quinolinone; 7-Methoxy-1-tosyl-1,2,3,4-tetrahydro-4-quinolone; 1-Tosyl-7-methoxy-3,4-dihydro-2H-quinolin-4-one; 4(1H)-Quinolinone, 2,3-dihydro-7-methoxy-1-[(4-methylphenyl)sulfonyl]-; 7-Methoxy-1-(p-tolylsulfonyl)-1,2,3,4-tetrahydro-4-quinolone; 901-90-6; NSC 163044
EINECS	Contact for details

Quality Control

Our production of 7-Methoxy-1-[(4-Methylphenyl)Sulfonyl]-2,3-Dihydroquinolin-4(1H)-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high chemical purity. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.