Description

α-Chloro-3'-Nitroacetophenone is a versatile and high-purity organic intermediate of significant commercial importance. Its unique molecular structure, featuring both a reactive α-chloro ketone and a nitroaryl group, makes it a critical building block for synthesizing more complex chemical entities. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing nitroaromatic or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators where its nitro and ketone functionalities are leveraged.
• Dye and Pigment Manufacturing: Serves as a building block for creating complex organic dyes, pigments, and colorants.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing novel molecules, studying reaction mechanisms, and developing new synthetic methodologies.
• Chemical Intermediate for Fine Chemicals: Employed in the multi-step synthesis of various fine chemicals and performance materials.

Basic Information

Product Name	α-Chloro-3'-Nitroacetophenone
CAS No.	99-47-8
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	2-Chloro-1-(3-nitrophenyl)ethanone; 3'-Nitro-α-chloroacetophenone; 2-Chloro-3'-nitroacetophenone; 1-(3-Nitrophenyl)-2-chloroethanone; ω-Chloro-3-nitroacetophenone; NSC 406908; 3-Nitro-ω-chloroacetophenone
EINECS	202-760-3

Quality Control

Our α-Chloro-3'-Nitroacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the highest standards of purity and consistency for industrial and research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and potential reactivity with strong oxidizers, ensure proper segregation from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	89 - 93 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.