Description

2-Chloro-5-Sulfamoylbenzoic Acid is a key organic intermediate characterized by its benzoic acid core substituted with both chloro and sulfamoyl functional groups. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists and process engineers in fine chemical manufacturing for creating active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of diuretics, particularly thiazide and high-ceiling diuretics like chlorothiazide.
• Agrochemical Synthesis: Used as a building block for developing herbicides and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing sulfonamide-based dyes and colorants.
• Research & Development: Employed in organic synthesis laboratories for exploring new chemical entities and reaction pathways.
• Chemical Synthesis: Utilized to introduce the chlorobenzoic acid and sulfonamide motifs into target molecules.

Basic Information

Product Name	2-Chloro-5-Sulfamoylbenzoic Acid
CAS No.	97-04-1
Molecular Formula	C7H6ClNO4S
Molecular Weight	235.64 g/mol
Synonyms	5-Chloro-2-sulfamoylbenzoic Acid; 2-Chloro-5-sulfamoylbenzoic acid; Benzoic acid, 2-chloro-5-sulfamoyl-; 4-Chloro-3-carboxybenzenesulfonamide; 5-Chloro-2-carboxybenzenesulfonamide; Chlorothiazide Intermediate; 97-04-1
EINECS	202-557-8

Quality Control

Our 2-Chloro-5-Sulfamoylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, IR, and other relevant tests. Our quality standards are designed to meet the rigorous demands of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product may be moisture-sensitive; ensure containers are kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.