Description

4-Bromo-3-Fluorophenyl Cyclopropyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated fluorophenyl ring with a strained cyclopropyl ketone moiety, enabling precise structural modifications. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry programs, particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated aromatic system.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to the electronic and steric properties imparted by the bromo and fluoro substituents.
• Material Science Precursor: Employed in the synthesis of monomers or additives for advanced polymers with tailored optical or electronic properties.
• Chemical Biology Probe Synthesis: Utilized as a building block for creating molecular probes and tags used in biochemical assay development and diagnostic research.

Basic Information

Product Name	4-Bromo-3-Fluorophenyl Cyclopropyl Ketone
CAS No.	898790-03-9
Molecular Formula	C10H8BrFO
Molecular Weight	243.07 g/mol
Synonyms	Cyclopropyl(4-bromo-3-fluorophenyl)methanone; 1-(4-Bromo-3-fluorophenyl)cyclopropan-1-one; 4-Bromo-3-fluorobenzoylcyclopropane; (4-Bromo-3-fluorophenyl)(cyclopropyl)ketone; 898790-03-9; 4-Bromo-3-fluoro cyclopropyl phenyl ketone
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorophenyl Cyclopropyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.