Description

Ethyl 8-[4-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate is a high-purity, complex organic ester featuring a spirocyclic ketal-protected amine moiety. This compound is a critical advanced intermediate in the synthesis of sophisticated active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel therapeutic agents and high-value functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging its unique molecular scaffold.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds and molecular probes used in biochemical and pharmacological research.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced polymers requiring specific functional group compatibility.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	Ethyl 8-[4-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate
CAS No.	898782-16-6
Molecular Formula	C24H35NO5
Molecular Weight	417.54 g/mol
Synonyms	8-[4-[(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]-8-oxooctanoic acid ethyl ester; Ethyl 8-oxo-8-[4-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]octanoate; 898782-16-6; AS-92338; SCHEMBL21805527; AKOS040759690; ZINC000257830995; CHEMBL3185269
EINECS	Contact for details

Quality Control

Our Ethyl 8-[4-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.