Description

5-(2-Iodophenyl)-5-Oxovaleric Acid is a high-purity iodinated aromatic keto acid building block. This compound is a critical intermediate in advanced organic synthesis, valued for its unique structure that enables the introduction of both an iodophenyl moiety and a reactive carboxylic acid terminus. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic disorders.
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Heck) due to the presence of the iodine atom, facilitating carbon-carbon bond formation.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	5-(2-Iodophenyl)-5-Oxovaleric Acid
CAS No.	898767-52-7
Molecular Formula	C11H11IO3
Molecular Weight	318.11 g/mol
Synonyms	5-(2-Iodobenzoyl)valeric Acid; 5-Oxo-5-(2-iodophenyl)pentanoic Acid; 2-Iodobenzoylbutyric Acid; 4-(2-Iodobenzoyl)butyric Acid; δ-Oxo-δ-(2-iodophenyl)valeric Acid; 898767-52-7; 5-(2-Iodophenyl)-5-oxopentanoic Acid
EINECS	Contact for details

Quality Control

Our 5-(2-Iodophenyl)-5-Oxovaleric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.