Description

2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyric Acid is a high-purity fluorinated organic building block of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring structurally complex molecules. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical manufacturers engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Material Science: Serves as a precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions at the ketone and carboxylic acid functional groups.
• Ligand & Catalyst Development: Utilized in the preparation of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyric Acid
CAS No.	898766-70-6
Molecular Formula	C12H13FO3
Molecular Weight	224.23 g/mol
Synonyms	3-Fluoro-β,β-dimethyl-γ-oxobenzenebutanoic Acid; 4-(3-Fluorophenyl)-2,2-dimethyl-4-oxobutanoic Acid; 2,2-Dimethyl-4-oxo-4-(3-fluorophenyl)butyric Acid; γ-Oxo-3-fluorobenzenebutanoic Acid, β,β-dimethyl-; Butanoic acid, 4-(3-fluorophenyl)-2,2-dimethyl-4-oxo-; CAS 898766-70-6
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4-(3-Fluorophenyl)-4-Oxobutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.