Description

3,3-Dimethyl-4'-Trifluoromethylbutyrophenone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its unique molecular structure, which combines a trifluoromethyl group with a butyrophenone backbone, making it a versatile intermediate for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for developing specialty polymers with specific thermal and chemical resistance properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex molecules via reactions like Friedel-Crafts acylation or nucleophilic addition.
• Fluorine Chemistry Research: An important compound for studying the effects of fluorine substitution on reactivity and physical properties in organic molecules.

Basic Information

Product Name	3,3-Dimethyl-4'-Trifluoromethylbutyrophenone
CAS No.	898764-76-6
Molecular Formula	C13H15F3O
Molecular Weight	244.26 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-[4-(trifluoromethyl)phenyl]butan-1-one; 4'-Trifluoromethyl-3,3-dimethylbutyrophenone; Butyrophenone, 3,3-dimethyl-4'-(trifluoromethyl)-; α,α-Dimethyl-4-(trifluoromethyl)butyrophenone; 3,3-Dimethyl-4-trifluoromethylbutyrophenone; 898764-76-6; Trifluoromethyl Dimethyl Butyrophenone
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-4'-Trifluoromethylbutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.