Description

1-(1,3-Dioxolan-2-Ylmethyl)-3-Methylbenzene is a specialized aromatic compound featuring a dioxolane-protected aldehyde functionality, making it a valuable synthon in advanced organic synthesis. This chemical matters for its role as a versatile, protected intermediate that enables precise chemical transformations under controlled conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the controlled introduction of benzyl or aldehyde moieties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its protected form offers synthetic advantages.
• Fine Chemical Production: Serves as a precursor in the manufacture of dyes, fragrances, and other specialty chemicals requiring specific aromatic substitution patterns.
• Academic & Industrial Research: Employed in methodological development and as a model compound in studies involving acetal protection/deprotection strategies and cross-coupling reactions.
• Material Science Precursor: Potential intermediate in the synthesis of monomers or ligands for advanced polymeric materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(1,3-Dioxolan-2-Ylmethyl)-3-Methylbenzene
CAS No.	898759-51-8
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	3-Methylbenzylaldehyde ethylene acetal; 1,3-Dioxolane, 2-[(3-methylphenyl)methyl]-; α-(3-Methylphenyl)-1,3-dioxolane-2-methanol; m-Tolualdehyde ethylene acetal; (3-Methylphenyl)acetaldehyde ethylene acetal; 2-[(3-Methylbenzyl)]-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our 1-(1,3-Dioxolan-2-Ylmethyl)-3-Methylbenzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), identity confirmation (by IR/NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.