Description

3-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-5-Fluorobenzophenone is a sophisticated organic intermediate featuring a benzophenone core functionalized with halogen and spirocyclic acetal-protected amine moieties. This compound matters as a key building block in the synthesis of complex molecules, particularly for pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring spirocyclic structural motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the benzophenone scaffold and halogen atoms contribute to biological activity.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function or protein-protein interactions.
• Material Science Precursor: Can be utilized in the development of specialty polymers or organic electronic materials due to its conjugated aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic Research: Employed in university and institutional laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-5-Fluorobenzophenone
CAS No.	898756-42-8
Molecular Formula	C25H27ClFNO3
Molecular Weight	443.94 g/mol
Synonyms	5-Fluoro-3-chloro-2'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 3-Chloro-5-fluoro-2'-[((1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl)]benzophenone; 898756-42-8; Benzophenone, 3-chloro-2'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-5-fluoro-; Spirocyclic-protected aminomethyl benzophenone derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-5-Fluorobenzophenone is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with each shipment. We support development and commercial projects with custom purity grades and documentation to meet specific regulatory or research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.