Description

2-Carboethoxy-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a sophisticated organic intermediate featuring a benzophenone core functionalized with both an ester group and a protected amino spirocycle. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. Its unique structure makes it essential for medicinal chemists and fine chemical manufacturers working on advanced therapeutic agents, such as protease inhibitors or other bioactive compounds that require specific spatial and electronic properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological or metabolic disorders.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design and synthesis of novel protease inhibitor drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities and optimize drug-like properties.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, specialized organic compounds.
• Bioconjugation & Probe Development: The reactive ketone and protected amine functionalities allow for further derivatization to create biochemical probes or labeled compounds for diagnostic applications.

Basic Information

Product Name	2-Carboethoxy-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898755-89-0
Molecular Formula	C24H27NO5
Molecular Weight	409.48 g/mol
Synonyms	Ethyl 2-[8-[[2-(Benzoyl)phenyl]methyl]-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]acetate; 2-Carboethoxy-2'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone; 898755-89-0; Benzophenone, 2'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)-2-(ethoxycarbonyl)-; 2-(Ethoxycarbonyl)-2'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 2-Carboethoxy-2'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.