Description

3-Bromo-2-Iodoquinoline is a high-value halogenated quinoline derivative, a crucial building block in advanced organic synthesis. Its unique bifunctional halogen pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used to develop new active ingredients for crop protection products, leveraging the quinoline scaffold's bioactivity.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED emitters and charge-transport molecules.
• Cross-Coupling Reactions: The bromo and iodo substituents provide distinct reactivity for sequential Suzuki, Stille, or Sonogashira cross-coupling reactions.
• Chemical Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry.

Basic Information

Item	Detail
Product Name	3-Bromo-2-Iodoquinoline
CAS No.	898559-23-4
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	2-Iodo-3-bromoquinoline; Quinoline, 3-bromo-2-iodo-; 3-Bromo-2-iodoquinoline; 898559-23-4; 3-Br-2-I-quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Iodoquinoline is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.