Description

4-Amino-3,3-Dimethyl-Butyric Acid Ethyl Ester Hydrochloride is a high-purity organic salt, primarily utilized as a critical pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, offering a protected amino acid derivative essential for peptide coupling and medicinal chemistry research. It is a key building block for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered β-amino acid moiety.
• Peptide Synthesis: Serves as a protected amino acid ester component in solid-phase and solution-phase peptide synthesis.
• Medicinal Chemistry Research: Used in the research and development of new drug candidates, especially in creating libraries of novel organic molecules.
• Agrochemical Synthesis: An intermediate in the production of advanced pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances.
• Bioconjugation Chemistry: Useful for modifying biomolecules due to its reactive amine group (as the HCl salt).

Basic Information

Product Name	4-Amino-3,3-Dimethyl-Butyric Acid Ethyl Ester Hydrochloride
CAS No.	898552-72-2
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	Ethyl 4-Amino-3,3-dimethylbutanoate Hydrochloride; 3,3-Dimethyl-4-aminobutanoic Acid Ethyl Ester Hydrochloride; 4-Amino-3,3-dimethylbutyric Acid Ethyl Ester HCl; Ethyl 3,3-Dimethyl-4-aminobutanoate Hydrochloride; 4-Amino-3,3-dimethyl-butanoic Acid Ethyl Ester Hydrochloride; ADBE HCl; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Amino-3,3-Dimethyl-Butyric Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.