Description

3-(tert-Butyl)-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazole-quinoline hybrid structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly for applications in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The structural motif is valuable for creating potential inhibitors of specific protein kinases involved in cancer and inflammatory diseases.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and bioorganic chemistry.

Basic Information

Product Name	3-(tert-Butyl)-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Amine
CAS No.	897373-62-5
Molecular Formula	C₁₆H₁₈N₄
Molecular Weight	266.34 g/mol
Synonyms	3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-amine; 1H-Pyrazol-5-amine, 3-(1,1-dimethylethyl)-1-(6-quinolinyl)-; 3-(tert-Butyl)-1-(6-quinolyl)-1H-pyrazol-5-amine; 3-tert-Butyl-1-(6-quinolyl)-1H-pyrazol-5-amine; 5-Amino-3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazole; 897373-62-5; 6-(5-Amino-3-tert-butyl-1H-pyrazol-1-yl)quinoline
EINECS	Contact for details

Quality Control

Our 3-(tert-Butyl)-1-(Quinolin-6-Yl)-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.