Description

Azetidine, 3-(Ethoxymethyl)-, Hydrochloride (1:1) is a high-purity, functionalized azetidine building block offered as a stable hydrochloride salt. This compound is of significant value in pharmaceutical research and development, particularly for medicinal chemists designing novel small molecule therapeutics. It serves as a key synthetic intermediate for constructing complex nitrogen-containing heterocycles, enabling the exploration of new chemical space in drug discovery programs targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the azetidine moiety, which can improve metabolic stability and pharmacokinetic properties.
• Heterocyclic Compound Synthesis: Serves as a versatile precursor for constructing more complex, fused-ring systems and spirocycles in organic synthesis.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Can be utilized to develop novel ligands for catalysis or as a component in organocatalysts.
• Chemical Biology Probes: Useful for creating tool compounds and probes to study biological pathways and protein function.

Basic Information

Product Name	Azetidine, 3-(Ethoxymethyl)-, Hydrochloride (1:1)
CAS No.	897019-61-3
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	3-(Ethoxymethyl)azetidine hydrochloride; 1-(Ethoxymethyl)-3-azetidine hydrochloride; Azetidine, 3-(ethoxymethyl)-, hydrochloride; 3-Azetidinemethanol, α-ethyl-, hydrochloride; 3-(Ethoxymethyl)azetidine HCl
EINECS	Contact for details

Quality Control

Our Azetidine, 3-(Ethoxymethyl)-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.