Description

3-Propoxy-Azetidine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its azetidine scaffold, a four-membered nitrogen heterocycle prized in medicinal chemistry for its role as a conformational constraint and bioisostere. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the potency, selectivity, and metabolic stability of lead compounds.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, or insecticides that utilize the azetidine moiety.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used to study biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of APIs (Active Pharmaceutical Ingredients).
• Academic & Industrial R&D: Fundamental research reagent in organic synthesis and methodology development focused on strained heterocycles.

Basic Information

Product Name	3-Propoxy-Azetidine Hydrochloride
CAS No.	897019-55-5
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	Azetidine, 3-propoxy-, hydrochloride (1:1); 3-Propoxyazetidine HCl; 3-Propoxy-azetidine hydrochloride; Azetidine, 3-propoxy-, monohydrochloride; 1-(Propoxy)azetidine hydrochloride; 3-Propoxyazetidine Hydrochloride Salt; 3-Propoxy-azetidine HCl salt
EINECS	Contact for details

Quality Control

Our 3-Propoxy-Azetidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.