Description

(S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-Methoxyphenyl)-3,3-Dimethyl-4-Oxoazetidin-2-Yloxy)-3,3,5'-Trimethylspiro[Azetidine-2,3'-Indol]-4-One is a high-purity, complex chiral spiro compound featuring a unique azetidinone-oxindole hybrid structure. This compound is of significant value as a key synthetic intermediate or a potential pharmacophore in advanced organic and medicinal chemistry research. It is primarily needed by pharmaceutical R&D organizations, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly for targeted diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Asymmetric Synthesis: Employed in the development of new chiral catalysts or ligands due to its defined stereocenters and complex architecture.
• Process Chemistry Development: Acts as a reference standard or an intermediate in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for studying novel organic reactions, heterocyclic chemistry, and the properties of spiro compounds.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays or in bioconjugation strategies, given its functionalizable structure.

Basic Information

Product Name	(S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-Methoxyphenyl)-3,3-Dimethyl-4-Oxoazetidin-2-Yloxy)-3,3,5'-Trimethylspiro[Azetidine-2,3'-Indol]-4-One
CAS No.	896746-40-0
Molecular Formula	C32H33N3O5
Molecular Weight	539.62 g/mol
Synonyms	(S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-methoxyphenyl)-3,3-dimethyl-4-oxoazetidin-2-yloxy)-3,3,5'-trimethylspiro[azetidine-2,3'-indol]-4-one; Spiro[azetidine-2,3'-indol]-4-one, 1-(4-methoxyphenyl)-2'-[(1R)-1-(4-methoxyphenyl)-3,3-dimethyl-4-oxo-2-azetidinyl]oxy]-3,3,5'-trimethyl-, (2'S)-; (S)-1-(p-Methoxyphenyl)-2'-((R)-1-(p-methoxyphenyl)-3,3-dimethyl-4-oxoazetidin-2-yloxy)-3,3,5'-trimethylspiro[azetidine-2,3'-indol]-4-one; Azetidine-oxindole spiro compound 896746-40-0; Chiral spiro azetidinone-oxindole hybrid
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with the standards expected by pharmaceutical and advanced research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.