Description

Acetamide, 2-[[3,4-Dihydro-6-(4-Morpholinyl)-4-Oxo-3-(2-Phenylethyl)-2-Quinazolinyl]Thio]-n-[(Tetrahydro-2-Furanyl)Methyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers engaged in developing next-generation drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in the synthesis pathway for potential kinase inhibitors and other targeted cancer therapies due to its quinazolinone core.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial labs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring high-purity, complex heterocyclic compounds.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Biochemical Research: May be utilized as a tool compound or probe in biochemical assays to study specific enzyme interactions.

Basic Information

Product Name	Acetamide, 2-[[3,4-Dihydro-6-(4-Morpholinyl)-4-Oxo-3-(2-Phenylethyl)-2-Quinazolinyl]Thio]-n-[(Tetrahydro-2-Furanyl)Methyl]-
CAS No.	896683-84-4
Molecular Formula	C27H32N4O3S
Molecular Weight	492.64 g/mol
Synonyms	2-({3,4-Dihydro-6-(morpholin-4-yl)-4-oxo-3-(2-phenylethyl)quinazolin-2-yl}thio)-N-[(oxolan-2-yl)methyl]acetamide; N-[(Tetrahydrofuran-2-yl)methyl]-2-{[6-(morpholin-4-yl)-4-oxo-3-(2-phenylethyl)-3,4-dihydroquinazolin-2-yl]thio}acetamide; 2-({3,4-Dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl}thio)-N-[(tetrahydro-2-furanyl)methyl]acetamide; 896683-84-4; Quinazolinone acetamide derivative; Tetrahydrofuranylmethyl acetamide quinazolinyl thioether
EINECS	Contact for details

Quality Control

Our Acetamide, 2-[[3,4-Dihydro-6-(4-Morpholinyl)-4-Oxo-3-(2-Phenylethyl)-2-Quinazolinyl]Thio]-n-[(Tetrahydro-2-Furanyl)Methyl]- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications. We support development and cGMP production with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.