Description

2-(4-Chlorophenyl)-3,6,8-Trimethylquinoline-4-Carboxylic Acid is a high-purity, multi-substituted quinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its complex molecular architecture, featuring chlorophenyl and carboxylic acid functionalities, makes it a valuable building block for creating sophisticated chemical entities. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing compounds with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, leveraging its quinoline core for bioactive molecule design.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a potential building block for electron-transport or host materials in OLED device fabrication due to its rigid, conjugated structure.
• Coordination Chemistry & Ligand Synthesis: The carboxylic acid group allows it to act as a ligand for metal complexes, useful in catalysis and material science applications.
• Chemical Research & Development: Employed as a standard or reagent in academic and industrial R&D for studying heterocyclic chemistry and structure-activity relationships.
• Dye & Pigment Intermediate: Functions as a precursor in the synthesis of specialized quinoline-based dyes and colorants for niche industrial applications.

Basic Information

Product Name	2-(4-Chlorophenyl)-3,6,8-Trimethylquinoline-4-Carboxylic Acid
CAS No.	895923-44-1
Molecular Formula	C19H16ClNO2
Molecular Weight	325.79 g/mol
Synonyms	4-Carboxy-2-(4-chlorophenyl)-3,6,8-trimethylquinoline; 2-(p-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid; 3,6,8-Trimethyl-2-(4-chlorophenyl)quinoline-4-carboxylic acid; Quinoline-4-carboxylic acid, 2-(4-chlorophenyl)-3,6,8-trimethyl-; 895923-44-1; 2-(4-Chlorophenyl)-3,6,8-trimethyl-4-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-(4-Chlorophenyl)-3,6,8-Trimethylquinoline-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.