Description

cis-3-Fluoropiperidin-4-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate featuring a fluorinated piperidine scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting G-protein-coupled receptors (GPCRs) and enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated, functionalized piperidine structure.
• CNS Drug Development: Serves as a precursor for compounds being investigated for neurological disorders, leveraging the pharmacokinetic benefits of fluorine substitution.
• Oncology Research: Employed in the construction of small-molecule inhibitors and targeted therapies.
• Chemical Biology: Utilized as a probe or labeling component in biochemical assays and diagnostic research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	cis-3-Fluoropiperidin-4-Yl)Methanol
CAS No.	895634-73-8
Molecular Formula	C6H12FNO
Molecular Weight	133.16 g/mol
Synonyms	(3R,4S)-3-Fluoropiperidin-4-ylmethanol; (3S,4R)-3-Fluoropiperidin-4-ylmethanol; cis-3-Fluoro-4-hydroxymethylpiperidine; 4-Piperidinemethanol, 3-fluoro-, (3R,4S)-rel-; 3-Fluoropiperidine-4-methanol; (cis)-3-Fluoropiperidin-4-ylmethanol; 895634-73-8; (3-Fluoropiperidin-4-yl)methanol
EINECS	Contact for details

Quality Control

Our cis-3-Fluoropiperidin-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.