Description

Rhodium(1+), [(1,2,5,6-η)-1,5-Cyclooctadiene][(2R,2'R,5R,5'R)-1,1'-(1,2-Ethanediyl)Bis[2,5-Bis(1-Methylethyl)Phospholane-κp]]-, Tetrafluoroborate(1-) (9Ci) is a high-value, chiral rhodium(I) complex featuring a DuPhos-type ligand, renowned for its exceptional performance in asymmetric catalysis. This compound is critical for enabling highly enantioselective transformations, particularly hydrogenation reactions, which are fundamental to the synthesis of complex chiral molecules. It is an indispensable tool for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to produce single-enantiomer intermediates and active ingredients with superior efficiency and selectivity.

Application

• Asymmetric Hydrogenation Catalyst: Primary application for the enantioselective reduction of prochiral olefins, enamides, and ketones to generate chiral centers with high enantiomeric excess (ee).
• Pharmaceutical Intermediate Synthesis: Production of chiral building blocks and active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Manufacturing: Synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators where biological activity is often specific to one enantiomer.
• Fine Chemical and Fragrance Production: Creation of high-value chiral compounds used in flavors, fragrances, and advanced materials.
• Methodology Development in Organic Synthesis: A benchmark catalyst for developing new asymmetric synthetic routes and protocols in academic and industrial research laboratories.
• Process Chemistry Optimization: Scaling up enantioselective hydrogenation processes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Item	Details
Product Name	Rhodium(1+), [(1,2,5,6-η)-1,5-Cyclooctadiene][(2R,2'R,5R,5'R)-1,1'-(1,2-Ethanediyl)Bis[2,5-Bis(1-Methylethyl)Phospholane-κp]]-, Tetrafluoroborate(1-) (9Ci)
CAS No.	895541-38-5
Molecular Formula	C34H58BF4P2Rh
Molecular Weight	706.45 g/mol
Synonyms	[(R,R)-Me-DuPhos)Rh(COD)]BF4; (R,R)-Me-DuPhos Rhodium(I) 1,5-cyclooctadiene Tetrafluoroborate; [Rh((R,R)-Me-DuPhos)(COD)]BF4; Rhodium(I)-(R,R)-1,2-Bis(2,5-dimethylphospholano)ethane(1,5-cyclooctadiene) tetrafluoroborate; (R,R)-2,2'-Bis(2,5-dimethylphospholanyl)-1,1'-biphenyl rhodium(I) COD tetrafluoroborate complex; Asymmetric hydrogenation catalyst Rh-MeDuPhos; DuPhos-Rh catalyst
EINECS	Contact for details

Quality Control

Every batch of our rhodium DuPhos catalyst is manufactured and tested under strict quality management protocols to ensure consistent, high-performance catalytic activity. We employ advanced analytical techniques including NMR, HPLC, and elemental analysis to verify chemical identity, chiral purity, and metal content. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric purity (where applicable), and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. The material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to preserve catalytic efficacy.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content (ICP-OES)	13.0 - 15.0 %
Solubility	Soluble in dichloromethane, acetone; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.