Description

8-((Trimethylsilyl)Ethynyl)Quinoline is a specialized organosilicon building block featuring a quinoline core functionalized with a trimethylsilyl-protected ethynyl group. This compound matters as a versatile intermediate in advanced organic synthesis, particularly valued for its role in cross-coupling reactions and the construction of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Key intermediate in pharmaceutical research for the synthesis of novel drug candidates and bioactive molecules.
• Building block for agrochemical development, used in creating new pesticides and herbicides.
• Precursor in material science for the preparation of organic semiconductors, ligands, and metal-organic frameworks (MOFs).
• Critical reagent in cross-coupling reactions such as Sonogashira, Heck, and Suzuki-Miyaura couplings.
• Used in academic and industrial R&D for methodological studies and library synthesis.
• Starting material for synthesizing fluorescent dyes and probes due to the quinoline fluorophore.
• Intermediate for creating specialty polymers and advanced organic coatings.

Basic Information

Product Name	8-((Trimethylsilyl)Ethynyl)Quinoline
CAS No.	895164-50-8
Molecular Formula	C₁₄H₁₇NSi
Molecular Weight	227.38 g/mol
Synonyms	8-[(Trimethylsilyl)ethynyl]quinoline; Quinoline, 8-[(trimethylsilyl)ethynyl]-; 8-(Trimethylsilylethynyl)quinoline; 8-Ethynylquinoline trimethylsilyl ether; TMS-ethynylquinoline; 8-(TMS-ethynyl)quinoline; 8-((Trimethylsilyl)ethynyl)quinoline; 8-Quinolinyltrimethylsilylacetylene
EINECS	Contact for details

Quality Control

Our 8-((Trimethylsilyl)Ethynyl)Quinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.