Description

2H-Pyrido[1,2-A]Pyrazine-1,8-Dione, 2-[(4-Fluorophenyl)Methyl]-3,4-Dihydro-9-Hydroxy-6-Methoxy- CAS NO 895133-63-8 is a high-purity, fluorinated heterocyclic compound belonging to the pyridopyrazinedione class. This molecule is of significant interest as a key advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel therapeutic agents and complex chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or precursor in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Reagent: Acts as a versatile fluorinated synthon for constructing complex heterocyclic systems in academic and industrial research laboratories.
• Biochemical Research: Potential application as a tool compound or probe for studying enzyme inhibition and biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value fluorinated compounds.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-1,8-Dione, 2-[(4-Fluorophenyl)Methyl]-3,4-Dihydro-9-Hydroxy-6-Methoxy-
CAS No.	895133-63-8
Molecular Formula	C₁₇H₁₅FN₂O₄
Molecular Weight	330.31 g/mol
Synonyms	9-Hydroxy-6-methoxy-2-[(4-fluorophenyl)methyl]-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; 2-[(4-Fluorobenzyl)-9-hydroxy-6-methoxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; 2-(4-Fluorobenzyl)-9-hydroxy-6-methoxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione; 895133-63-8; Fluorinated Pyridopyrazinedione Derivative
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical-grade material is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.