Description

5,6,7,8-Tetrahydro-2,7-Naphthyridin-3-Ol is a heterocyclic organic compound featuring a fused naphthyridine core, which serves as a critical synthetic intermediate and pharmacophore in modern chemical research. Its unique bicyclic structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Serves as a chelating ligand precursor in catalysis and material science for metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and receptor binding interactions.
• Fine Chemical Synthesis: Building block for creating complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: Essential material for method development and exploratory research in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	5,6,7,8-Tetrahydro-2,7-Naphthyridin-3-Ol
CAS No.	893842-96-1
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	3-Hydroxy-5,6,7,8-tetrahydro-2,7-naphthyridine; 5,6,7,8-Tetrahydro-2,7-naphthyridin-3-ol; 2,7-Naphthyridin-3-ol, 5,6,7,8-tetrahydro-; THN-3-ol; 3-Hydroxytetrahydro-2,7-naphthyridine
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2,7-Naphthyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.