Description

3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Ol is a high-purity biphenyl derivative characterized by a phenolic hydroxyl group and a trifluoromethyl substituent. This unique molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for organic synthesis. It is primarily used by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS, anti-inflammatory, or metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for creating new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced electronic materials, where the biphenyl core and fluorine atoms contribute to desired electronic and mesomorphic properties.
• Organic Ligand & Catalyst Development: Acts as a building block for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Resin Modification: Employed to introduce fluorinated aromatic units into polymer chains to enhance thermal stability, chemical resistance, and surface properties.
• Academic & Contract Research: A critical reagent for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Ol
CAS No.	893738-60-8
Molecular Formula	C₁₃H₉F₃O
Molecular Weight	238.21 g/mol
Synonyms	[1,1'-Biphenyl]-2-ol, 3'-(trifluoromethyl)-; 2-Hydroxy-3'-(trifluoromethyl)biphenyl; 3'-(Trifluoromethyl)biphenyl-2-ol; 2-(3-(Trifluoromethyl)phenyl)phenol; 3'-Trifluoromethyl-2-hydroxybiphenyl; 2-Hydroxy-3'-trifluoromethyl-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Ol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.