Description

6-(Thiophen-3-Yl)Picolinic Acid is a high-purity heterocyclic building block of significant interest in advanced chemical synthesis. This compound is valued for its unique molecular architecture, which combines picolinic acid and thiophene moieties to create a versatile scaffold for pharmaceutical and materials research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs) due to its carboxylic acid and nitrogen donor sites.
• Material Science: Employed in the research and development of organic semiconductors, conductive polymers, and other electronic materials where the thiophene unit is advantageous.
• Chemical Biology: Utilized as a molecular probe or tag in bioconjugation and proteomics research.
• Custom Synthesis & Scale-Up: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	6-(Thiophen-3-Yl)Picolinic Acid
CAS No.	893723-81-4
Molecular Formula	C10H7NO2S
Molecular Weight	205.23 g/mol
Synonyms	3-(6-Carboxypyridin-2-yl)thiophene; 2-Pyridinecarboxylic acid, 6-(3-thienyl)-; 6-(3-Thienyl)-2-pyridinecarboxylic acid; 6-(Thiophen-3-yl)pyridine-2-carboxylic acid; 6-(3-Thienyl)picolinic acid; 893723-81-4; AI3-63500; AKOS040751830; BCP34033; CS-W009767; FT-0773299; NS00023817; STL514210
EINECS	Contact for details

Quality Control

Every batch of 6-(Thiophen-3-Yl)Picolinic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. Our products are produced to meet the exacting standards required for research and development, with typical purity grades exceeding 97% (HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile to ensure batch-to-batch consistency and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.