Description

[1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Chloro-3'-(Trifluoromethyl)- is a high-value biphenyl derivative and a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a carboxylic acid group and halogenated trifluoromethyl substituents, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a key building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the biphenyl core and halogen substituents.
• Ligand and Catalyst Development: Used in research to create specialized ligands for metal-organic frameworks (MOFs) or catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, due to the conjugated biphenyl system.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Chloro-3'-(Trifluoromethyl)-
CAS No.	893637-97-3
Molecular Formula	C14H8ClF3O2
Molecular Weight	300.66 g/mol
Synonyms	4'-Chloro-3'-(trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid; 3-Biphenylcarboxylic acid, 4'-chloro-3'-(trifluoromethyl)-; 4'-Chloro-3'-trifluoromethylbiphenyl-3-carboxylic acid; 4'-Chloro-3'-(trifluoromethyl)biphenyl-3-carboxylic acid; 4'-Chloro-3'-trifluoromethyl-3-biphenylcarboxylic acid
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Carboxylic Acid, 4'-Chloro-3'-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.