Description

2-Chloro-4-Fluoroquinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of both chloro and fluoro substituents onto the quinoline scaffold. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create compounds with enhanced biological activity and optimized physicochemical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates and other therapeutic agents.
• Agrochemical Synthesis: Building block for developing new generation pesticides, herbicides, and fungicides with improved efficacy.
• Material Science Research: Used in the creation of organic semiconductors, ligands for catalysis, and fluorescent dyes or markers.
• Chemical Biology Probes: Serves as a scaffold for designing molecular probes to study biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	2-Chloro-4-Fluoroquinoline
CAS No.	893620-30-9
Molecular Formula	C9H5ClFN
Molecular Weight	181.59 g/mol
Synonyms	2-Chloro-4-fluoroquinoline; 4-Fluoro-2-chloroquinoline; Quinoline, 2-chloro-4-fluoro-; 893620-30-9; 2-Chloro-4-fluoro-quinoline; FCQ
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoroquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and development needs. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.