Description

Spiro[2.5]Octan-5,7-Dione CAS NO 893411-52-4 is a specialized spirocyclic diketone compound, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique bridged bicyclic structure makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical synthesis. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring spirocyclic or strained ring systems for enhanced biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where its unique carbon skeleton contributes to new modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions, ring-expansion reactions, and as a scaffold for constructing natural product analogs and complex heterocycles.
• Ligand and Catalyst Development: Utilized as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	Spiro[2.5]Octan-5,7-Dione
CAS No.	893411-52-4
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	Spiro[2.5]octane-5,7-dione; 5,7-Dioxaspiro[2.5]octane; 1,4-Dioxaspiro[2.5]octane-5,7-dione; Bicyclo[3.1.0]hexane-2,4-dione; Spirocyclopropane-1,2'-cyclohexane-4',6'-dione
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octan-5,7-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.