Description

8-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester is a high-purity, functionalized quinoline derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials and anticancer agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the chloroquinoline core.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Intermediate in the production of functionalized quinoline derivatives for optoelectronic applications.
• Chemical Biology Probes: Utilized to develop fluorescent tags or molecular probes for biological imaging and diagnostic research.
• Academic & Contract Research: Essential reagent for method development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	8-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester
CAS No.	892874-60-1
Molecular Formula	C₁₅H₁₄ClNO₄
Molecular Weight	307.73 g/mol
Synonyms	Diethyl 8-Chloroquinoline-2,3-Dicarboxylate; 8-Chloro-2,3-quinolinedicarboxylic Acid Diethyl Ester; 8-Chloroquinoline-2,3-dicarboxylic Acid Diethyl Ester; Ethyl 8-Chloro-2,3-quinolinedicarboxylate; 2,3-Bis(ethoxycarbonyl)-8-chloroquinoline; 8-Chloro-quinoline-2,3-dicarboxylic acid diethyl ester; 892874-60-1; 8-Chloro-2,3-quinolinedicarboxylic acid, diethyl ester
EINECS	Contact for details

Quality Control

Our 8-Chloroquinoline-2,3-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.