Description

7-Bromo-2-Chloroquinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring bromine, chlorine, and nitrile substituents on a quinoline core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive halogen sites.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the quinoline scaffold into more complex structures.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and colorants.

Basic Information

Item	Details
Product Name	7-Bromo-2-Chloroquinoline-3-Carbonitrile
CAS No.	892874-32-7
Molecular Formula	C10H4BrClN2
Molecular Weight	267.51 g/mol
Synonyms	2-Chloro-7-bromoquinoline-3-carbonitrile; 7-Bromo-2-chloro-3-cyanoquinoline; 3-Cyano-7-bromo-2-chloroquinoline; Quinoline, 7-bromo-2-chloro-3-cyano-; 892874-32-7; 7-Bromo-2-chloroquinoline-3-carbonitrile; 2-Chloro-7-bromoquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Chloroquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.