Description

3-(6,8-Dioxo-5,8-Dihydro[1,3]Dioxolo[4,5-G]Quinazolin-7(6H)-Yl)Propanoicacid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic quinazolinone structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation small molecule drugs and for process optimization in active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzymes or receptors.
• Oncology Research: Used in the development of novel kinase inhibitors and other targeted cancer therapies due to its quinazolinone core, a privileged scaffold in medicinal chemistry.
• Antiviral Drug Development: Serves as a building block for compounds being investigated for their activity against various viral pathogens.
• Biochemical Tool Compound: Utilized in academic and industrial research to study biological pathways and for high-throughput screening assays.
• Process Chemistry & Scale-Up: Employed by fine chemical manufacturers for route scouting, optimization, and the commercial-scale production of APIs.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(6,8-Dioxo-5,8-Dihydro[1,3]Dioxolo[4,5-G]Quinazolin-7(6H)-Yl)Propanoicacid
CAS No.	892293-07-1
Molecular Formula	C₁₄H₁₀N₂O₆
Molecular Weight	302.24 g/mol
Synonyms	7-(2-Carboxyethyl)-5,8-dihydro[1,3]dioxolo[4,5-g]quinazoline-6,8-dione; 3-((6,8-Dioxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinazolin-7(6H)-yl))propanoic acid; Propanoic acid, 3-(6,8-dioxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinazolin-7(6H)-yl)-; [1,3]Dioxolo[4,5-g]quinazoline-7(6H)-propanoic acid, 5,8-dihydro-6,8-dioxo-; CAS 892293-07-1
EINECS	Contact for details

Quality Control

Our 3-(6,8-Dioxo-5,8-Dihydro[1,3]Dioxolo[4,5-G]Quinazolin-7(6H)-Yl)Propanoicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.