Description

2-Bromo-6-Chloroquinoline CAS NO 891842-50-5 is a high-purity halogenated quinoline derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its dual reactive sites, which enable precise functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, serving as a key building block for active pharmaceutical ingredients (APIs), functional dyes, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antiviral agents, and other biologically active quinoline-based compounds.
• Agrochemical Synthesis: Used as a building block for creating advanced fungicides, herbicides, and pesticides that require specific halogenated quinoline scaffolds for enhanced efficacy.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex substituents.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and pigments with specific colorfastness and light-absorption properties.

Basic Information

Product Name	2-Bromo-6-Chloroquinoline
CAS No.	891842-50-5
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	6-Chloro-2-bromoquinoline; Quinoline, 2-bromo-6-chloro-; 2-Bromo-6-chloroquinoline; 891842-50-5; 6-Chloro-2-bromo-quinoline; 2-Brom-6-chlorchinolin (German); 2-ブロモ-6-クロロキノリン (Japanese)
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.