Description

3-(2-Bromo-4-Methoxyphenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly due to the presence of the imidazothiazole core and functional carboxylic acid group. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for use in targeted synthesis programs.

Application

This specialized intermediate serves as a critical building block in several high-value chemical synthesis pathways. Key application areas include:

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Heterocyclic Compound Synthesis: Serves as a precursor for the development of more complex imidazo[2,1-b]thiazole derivatives with tailored biological activities.
• Bioconjugation & Probe Development: The carboxylic acid functionality allows for coupling to amines, enabling the creation of labeled probes or conjugate molecules for biological studies.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection products.
• Material Science: Exploration of its use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(2-Bromo-4-Methoxyphenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid
CAS No.	891773-68-5
Molecular Formula	C13H9BrN2O3S
Molecular Weight	353.19 g/mol
Synonyms	3-(2-Bromo-4-methoxyphenyl)imidazo[2,1-b][1,3]thiazole-6-carboxylic acid; Imidazo[2,1-b]thiazole-6-carboxylic acid, 3-(2-bromo-4-methoxyphenyl)-; 891773-68-5; 3-(2-Bromo-4-methoxyphenyl)-6-carboxyimidazo[2,1-b]thiazole; 6-Carboxy-3-(2-bromo-4-methoxyphenyl)imidazo[2,1-b]thiazole
EINECS	Contact for details

Quality Control

Our production of 3-(2-Bromo-4-Methoxyphenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistency and reliability for research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.