Description

Methyl (E)-(3S)-3-Amino-5-Methylhex-1-Enyl Sulfone Hydrochloride is a high-purity, chiral sulfone hydrochloride salt, serving as a critical advanced pharmaceutical intermediate. Its value lies in its defined stereochemistry and functional groups, which are essential for constructing complex bioactive molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for process chemistry and route scouting.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce the (3S)-amino sulfone moiety into target molecules, leveraging its defined stereocenter.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the preparation of more complex, proprietary compounds under contract research and manufacturing (CRAM) agreements.

Basic Information

Product Name	Methyl (E)-(3S)-3-Amino-5-Methylhex-1-Enyl Sulfone Hydrochloride
CAS No.	890660-04-5
Molecular Formula	C8H18ClNO2S
Molecular Weight	227.75 g/mol
Synonyms	(3S)-3-Amino-5-methyl-1-hexenyl methyl sulfone hydrochloride; (E)-Methyl (3S)-3-amino-5-methylhex-1-enyl sulfone hydrochloride; (E)-(3S)-3-Amino-5-methyl-1-hexenyl methyl sulfone HCl; Methyl (E)-(3S)-3-amino-5-methylhex-1-enylsulfone hydrochloride; (3S)-3-Amino-5-methylhex-1-enyl methyl sulfone hydrochloride (E)-; 890660-04-5; Methyl (E)-(3S)-3-Amino-5-Methyl-1-Hexenyl Sulfone HCl
EINECS	Contact for details

Quality Control

Our Methyl (E)-(3S)-3-Amino-5-Methylhex-1-Enyl Sulfone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.