Description

5-Hydrazino-2-(Trifluoromethyl)-1,6-Naphthyridine is a high-value, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity of the hydrazino group combined with the electron-deficient naphthyridine core, making it a versatile precursor for constructing complex nitrogen-containing scaffolds. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly as a key intermediate in medicinal chemistry programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced organic electronic materials or metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Employed to create labeled compounds or probes for studying biological pathways and target engagement.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: A starting point for custom manufacturing and process development for clients requiring specific, complex molecular architectures.

Basic Information

Product Name	5-Hydrazino-2-(Trifluoromethyl)-1,6-Naphthyridine
CAS No.	890302-19-9
Molecular Formula	C9H6F3N5
Molecular Weight	241.17 g/mol
Synonyms	2-(Trifluoromethyl)-1,6-naphthyridine-5-hydrazine; 5-Hydrazinyl-2-(trifluoromethyl)-1,6-naphthyridine; 1,6-Naphthyridine, 5-hydrazino-2-(trifluoromethyl)-; 890302-19-9; 5-Hydrazino-2-trifluoromethyl-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 5-Hydrazino-2-(Trifluoromethyl)-1,6-Naphthyridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.