Description

8-Bromo-5-Chloro-2-(Trifluoromethyl)-1,6-Naphthyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex halogenated and trifluoromethylated structure makes it a valuable intermediate for constructing novel molecular architectures with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the naphthyridine core.
• Material Science Precursor: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds for client projects.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	8-Bromo-5-Chloro-2-(Trifluoromethyl)-1,6-Naphthyridine
CAS No.	890301-89-0
Molecular Formula	C9H3BrClF3N2
Molecular Weight	311.48 g/mol
Synonyms	8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine; 1,6-Naphthyridine, 8-bromo-5-chloro-2-(trifluoromethyl)-; 8-Bromo-5-chloro-2-trifluoromethyl-1,6-naphthyridine; 890301-89-0; BCTN (abbreviation); 2-(Trifluoromethyl)-8-bromo-5-chloro-1,6-naphthyridine; 5-Chloro-8-bromo-2-(trifluoromethyl)-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Chloro-2-(Trifluoromethyl)-1,6-Naphthyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support custom synthesis and can tailor specifications, including chiral purity, to meet specific project requirements for preclinical and process development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.