Description

1H-Indole-3-Carboxylic Acid, 6-[(6-Amino-4-Pyrimidinyl)Oxy]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-pyrimidine hybrid structure. This compound matters for its critical role in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise building block to develop next-generation small molecule drugs and explore new biochemical pathways.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a standard or probe in enzymatic studies and structure-activity relationship (SAR) investigations due to its heterocyclic scaffold.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing complex molecules with potential biological activity, leveraging its reactive carboxylic acid and amino-pyrimidine functional groups.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents with specific modes of action.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid, 6-[(6-Amino-4-Pyrimidinyl)Oxy]-
CAS No.	890130-07-1
Molecular Formula	C13H10N4O3
Molecular Weight	270.24 g/mol
Synonyms	6-[(6-Aminopyrimidin-4-yl)oxy]-1H-indole-3-carboxylic acid; 6-(6-Amino-4-pyrimidinyloxy)indole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 6-[(6-amino-4-pyrimidinyl)oxy]-; 890130-07-1; 6-(6-Amino-pyrimidin-4-yloxy)-1H-indole-3-carboxylic acid; 6-((6-Aminopyrimidin-4-yl)oxy)-1H-indole-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid, 6-[(6-Amino-4-Pyrimidinyl)Oxy]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.