Description

2-(4-Methylpiperidin-1-Yl)-3-Nitrobenzoic Acid CAS NO 890091-66-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-substituted benzoic acid structure. This compound is essential for synthetic chemists developing novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a critical building block for complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its nitro and carboxylic acid functional groups.
• Ligand and Catalyst Development: Serves as a building block for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, pigments, and other performance chemicals requiring specific aromatic substitutions.

Basic Information

Product Name	2-(4-Methylpiperidin-1-Yl)-3-Nitrobenzoic Acid
CAS No.	890091-66-4
Molecular Formula	C14H18N2O4
Molecular Weight	278.31 g/mol
Synonyms	3-Nitro-2-(4-methyl-1-piperidinyl)benzoic Acid; 2-(4-Methyl-1-piperidinyl)-3-nitrobenzoic Acid; Benzoic acid, 3-nitro-2-(4-methyl-1-piperidinyl)-; 890091-66-4; 2-(4-Methylpiperidino)-3-nitrobenzoic Acid; 3-Nitro-2-(4-methylpiperidino)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperidin-1-Yl)-3-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.