Description

4-Chloro-2-Cyclohexyl-1H-Imidazo[4,5-C]Quinoline is a high-purity, advanced pharmaceutical intermediate belonging to the fused imidazoquinoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents, particularly within immunology and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Toll-like receptor (TLR) agonists and other immunomodulatory drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Reagent: Used in biochemical assays to study immune response pathways and cellular signaling mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules for biological evaluation.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge research in immunopharmacology.

Basic Information

Product Name	4-Chloro-2-Cyclohexyl-1H-Imidazo[4,5-C]Quinoline
CAS No.	890087-03-3
Molecular Formula	C16H16ClN3
Molecular Weight	285.77 g/mol
Synonyms	4-Chloro-2-cyclohexyl-1H-imidazo[4,5-c]quinoline; 2-Cyclohexyl-4-chloro-1H-imidazo[4,5-c]quinoline; 1H-Imidazo[4,5-c]quinoline, 4-chloro-2-cyclohexyl-; TLR7/8 Agonist Intermediate; Imidazoquinoline Derivative; 890087-03-3; UNII-9F8P8G8V4R
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Cyclohexyl-1H-Imidazo[4,5-C]Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.