Description

n-Hydroxy-6-Chloro-1H-Indole-3-Carboxamidine is a specialized heterocyclic building block featuring a reactive amidoxime functional group. This compound matters as a versatile synthetic intermediate, enabling the construction of complex molecular architectures for pharmaceutical and agrochemical research. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to optimize lead compounds.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Complex Ligand Preparation: The amidoxime moiety can be leveraged to create chelating agents or catalysts for metal-organic chemistry.

Basic Information

Product Name	n-Hydroxy-6-Chloro-1H-Indole-3-Carboxamidine
CAS No.	889942-64-7
Molecular Formula	C9H8ClN3O
Molecular Weight	209.63 g/mol
Synonyms	6-Chloro-1H-indole-3-carboximidamide, N-hydroxy-; 6-Chloro-N-hydroxy-1H-indole-3-carboxamidine; 6-Chloroindole-3-carboxamidoxime; 3-Amidoxime-6-chloroindole; 6-Chloro-3-(N-hydroxyamidino)indole; 6-Chloro-1H-indole-3-carboxamidine, N-hydroxy-; 889942-64-7; 6-Chloroindole-3-carboximidic acid, N-hydroxy- amide
EINECS	Contact for details

Quality Control

Our n-Hydroxy-6-Chloro-1H-Indole-3-Carboxamidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.