Description

5-Amino-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized organic molecules used in specialty chemical applications.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	5-Amino-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-5-Carboxylic Acid
CAS No.	889941-69-9
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	5-Amino-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxylic acid; 5-Amino-5,6,7,8,9,10-hexahydrobenzocycloheptene-5-carboxylic acid; 5-Aminobenzocycloheptene-5-carboxylic acid; 5-Carboxy-5-amino-6,7,8,9-tetrahydro-5H-benzocycloheptene; 5H-Benzocycloheptene-5-carboxylic acid, 5-amino-6,7,8,9-tetrahydro-
EINECS	Contact for details

Quality Control

Our 5-Amino-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.