Description

4-p-Tolyl-Tetrahydro-Pyran-4-Carboxylic Acid is a high-purity organic building block and advanced pharmaceutical intermediate of significant commercial interest. Its unique structure, featuring both a tetrahydro-pyran ring and a carboxylic acid group, makes it a versatile synthon for constructing complex molecules in medicinal chemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development and production of new herbicides, fungicides, or plant growth regulators.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale operations.
• Material Science: Potential monomer or additive in the research of specialty polymers with tailored properties.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Product Name	4-p-Tolyl-Tetrahydro-Pyran-4-Carboxylic Acid
CAS No.	889940-11-8
Molecular Formula	C14H16O3
Molecular Weight	232.28 g/mol
Synonyms	4-(4-Methylphenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(p-Tolyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(4-Methylphenyl)oxane-4-carboxylic acid; 4-Tolyl-tetrahydropyran-4-carboxylic acid; 889940-11-8; 4-(4-Methylphenyl)tetrahydropyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-p-Tolyl-Tetrahydro-Pyran-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.