Description

4-Bromo-3-Fluoro-2-Nitrophenol is a halogenated nitrophenol derivative, a versatile and high-purity organic building block essential for advanced chemical synthesis. Its unique structure, featuring bromine, fluorine, and nitro functional groups on a phenolic ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its nitro and phenolic functionalities.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing substituted phenolic motifs into larger molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Nitrophenol
CAS No.	889939-22-4
Molecular Formula	C6H3BrFNO3
Molecular Weight	236.00 g/mol
Synonyms	2-Nitro-4-bromo-3-fluorophenol; 3-Fluoro-4-bromo-2-nitrophenol; Phenol, 4-bromo-3-fluoro-2-nitro-; 4-Bromo-3-fluoro-2-nitro-phenol
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoro-2-Nitrophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.