Description

3,4-Dihydro-7-(4-Hydroxybutoxy)-2(1H)-Quinolinone is a high-purity synthetic organic compound belonging to the quinolinone class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), where consistent quality and reliable supply are paramount. This product is essential for research and development laboratories and manufacturing facilities in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• API Synthesis: Used as a core structural unit for constructing complex Active Pharmaceutical Ingredients (APIs) requiring the quinolinone pharmacophore.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition, receptor binding, and other pharmacological mechanisms.
• Process Chemistry Development: Serves as a standard or starting material for scaling up and optimizing synthetic routes in pilot plants and commercial production.
• Fine Chemical Production: Utilized in the manufacture of other high-value specialty chemicals and complex organic molecules.

Basic Information

Product Name	3,4-Dihydro-7-(4-Hydroxybutoxy)-2(1H)-Quinolinone
CAS No.	889443-20-3
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	7-(4-Hydroxybutoxy)-3,4-dihydro-2(1H)-quinolinone; 7-(4-Hydroxybutoxy)-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 3,4-dihydro-7-(4-hydroxybutoxy)-; 889443-20-3; Quinolinone derivative intermediate; 7-(4-Hydroxybutoxy)carbostyril; Tetrahydroquinolinone derivative
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-7-(4-Hydroxybutoxy)-2(1H)-Quinolinone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.