Description

2-(4-Bromophenyl)-2-{[(tert-Butoxy)Carbonyl]Amino}Propanoic Acid is a high-purity, protected amino acid derivative featuring a bromophenyl group and a Boc-protected amine, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where controlled stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Peptidomimetics & Constrained Peptides: Used to introduce non-natural, sterically hindered amino acid residues into peptide backbones to enhance stability, bioavailability, and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or as a building block for functional materials.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects at various scales, from research to pilot plant.

Basic Information

Product Name	2-(4-Bromophenyl)-2-{[(tert-Butoxy)Carbonyl]Amino}Propanoic Acid
CAS No.	888970-79-4
Molecular Formula	C₁₄H₁₈BrNO₄
Molecular Weight	344.20 g/mol
Synonyms	Boc-4-Bromo-DL-phenylalanine; 2-[(tert-Butoxycarbonyl)amino]-2-(4-bromophenyl)propanoic acid; N-Boc-2-amino-2-(4-bromophenyl)propionic acid; (RS)-2-((tert-Butoxycarbonyl)amino)-2-(4-bromophenyl)propanoic acid; 2-Amino-2-(4-bromophenyl)propanoic acid N-Boc derivative; N-(tert-Butoxycarbonyl)-4-bromo-DL-phenylalanine; Boc-4-Br-Phe-OH; 888970-79-4
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-2-{[(tert-Butoxy)Carbonyl]Amino}Propanoic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, chiral purity (if applicable), and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.