Description

4-(4-Nitrobenzylamino)Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its functionalized piperidine core.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom synthesis projects and scale-up services under cGMP or ISO standards.

Basic Information

Product Name	4-(4-Nitrobenzylamino)Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	888944-25-0
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-Boc-4-[(4-nitrophenyl)methylamino]piperidine; tert-Butyl 4-[(4-nitrobenzyl)amino]piperidine-1-carboxylate; 4-[(4-Nitrobenzyl)amino]-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 4-[(4-nitrobenzyl)amino]-1-piperidinecarboxylate; 4-(4-Nitrobenzylamino)piperidine-1-carboxylic acid tert-butyl ester; N-(4-Nitrobenzyl)-N-(1-Boc-piperidin-4-yl)amine; Boc-4-(4-nitrobenzylamino)piperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrobenzylamino)Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.