Description

Bis(Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine)Dichloropalladium(II) is a highly specialized, air-stable palladium catalyst featuring a bulky, electron-rich phosphine ligand, which is critical for facilitating challenging cross-coupling reactions. This compound matters because it offers superior catalytic activity and selectivity, particularly for C-C and C-N bond formations involving sterically hindered substrates, leading to higher yields and cleaner reaction profiles in advanced synthesis. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for constructing complex molecular architectures. The product is supplied under an inert atmosphere to ensure its catalytic integrity and is identified by CAS No. 887919-35-9.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions in the production of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of complex, nitrogen-containing herbicides, fungicides, and insecticides.
• Materials Science R&D: Enables the construction of conjugated polymers and organic electronic materials through efficient C-C coupling.
• Academic & Industrial Research: A valuable tool for methodological development and exploring new reaction pathways in organic synthesis.
• Fine Chemical Production: Catalyzes the synthesis of specialty chemicals, flavors, and fragrances requiring precise bond formation.

Basic Information

Product Name	Bis(Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine)Dichloropalladium(II)
CAS No.	887919-35-9
Molecular Formula	C36H60Cl2N2P2Pd
Molecular Weight	768.13 g/mol
Synonyms	Bis[di-tert-butyl(4-dimethylaminophenyl)phosphine]dichloropalladium; Pd-132; DavePhos Palladium(II) Chloride Dimer; Dichlorobis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium; [Pd(AmPhos)2Cl2]; AmPhos Palladium Catalyst; Palladium(II) chloride bis[di-tert-butyl(4-dimethylaminophenyl)phosphine] complex
EINECS	Contact for details

Quality Control

Our Bis(Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine)Dichloropalladium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality management system supports compliance with cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; exposure to air and moisture will degrade its catalytic activity. Keep the original container sealed and allow it to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Palladium (Pd) Content	13.8 - 14.2 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.